[Coffeeseminar] Journal club 30.5. 09:05 " "

[Aaro Salosensaari]

And hello again,

as Noora helpfully reminded just a minute ago, next Thursday is a 
holiday (helatorstai), and 6.6 we have an another internal meet, so the 
Journal Club presentation announced below will be moved to 13.6.2019.

On 23.5.2019 13.52, Aaro Salosensaari wrote:
> Hello,
>
> in next week's journal club (30.5.2019 ~09:05, in 2nd floor meeting 
> room), I will present following advance publication:
>
> Lee, M., Han, S. W. & Seok, J. Prediction of survival risks with 
> adjusted gene expression through risk-gene networks. /Bioinformatics/ 
> https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btz399/5490203 
> <https://doi.org/10.1093/bioinformatics/btz399>
>
> A couple of points of interest
>
> * includes nice overview of traditional Cox-LASSO survival with 
> variable selection
>
> * recursive network construction by neighborhood search was a news 
> concept to be and I thought it was quite interesting on its own
>
> * "data adjustment" sounds weird, but in practice the authors propose 
> to project the data to simpler linear model structure induced by the 
> network, which at least conceptually sounds surprisingly similar but 
> maybe numerically simpler than Bayesian projective inference variable 
> selection which according Piironen, Paasiniemi and Vehtari 2018 
> https://arxiv.org/abs/1810.02406 works well for prediction and feature 
> selection
>
> - best,
>
>  Aaro
>
-- 
Aaro Salosensaari
Jatko-opiskelija / PhD student
Lahti Lab, https://openresearchlabs.github.io
University of Turku
aaro.salosensaari at utu.fi